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Arch Intern Med. 1986 Aug;146(8):1624-5. Hypersensitivity caused by synthetic thyroid hormones in a hypothyroid patient with Hashimoto's thyroiditis.Shibata H, Hayakawa H, Hirukawa M, Tadokoro K, Ogata E. A 63-year-old hypothyroid woman with Hashimoto's thyroiditis developed fever, eosinophilia, and liver dysfunction in response to replacement doses of triiodothyronine, or L-thyroxine. The symptoms disappeared on cessation of the replacement therapy. Lymphocyte stimulation tests showed high stimulation indexes for both hormones. After an interval of four months, when the patient became severely hypothyroid, treatment with triiodothyronine on a slowly increasing dose program was tried and resulted in a good control without ill response at this time. This observation indicates that, under certain pathologic conditions, hypersensitivity may be induced to thyroid hormones administered exogenously. Ponadto opisano jeszcze 2 nowe przypadki "alergii" na Levothyroxin: 1: Ann Allergy Asthma Immunol. 2008 May;100(5):513-4.Links Immediate-type hypersensitivity reaction to levothyroxine and desensitization.Sala A, Labrador-Horrillo M, Guilarte M, Luengo O, Rueda M, Cardona V. 2. Ann Allergy Asthma Immunol. 2003 Oct;91(4):337-41.Links Levothyroxine anaphylaxis? Vocal cord dysfunction mimicking an anaphylactic drug reaction.Nugent JS, Nugent AL, Whisman BA,